The α-Ketoglutarate Dehydrogenase (α-KGDH) Activity Assay Kit is widely used in biochemical research to measure the activity of the α-KGDH enzyme, a key component of the tricarboxylic acid (TCA) cycle. This kit is essential for studying cellular metabolism, particularly in understanding how cells generate energy through oxidative processes. Researchers use it to investigate mitochondrial function and dysfunction, which is crucial in studies related to metabolic disorders, neurodegenerative diseases, and cancer. It is also employed in drug discovery and development to screen compounds that modulate mitochondrial activity or target metabolic pathways. Additionally, the kit is valuable in assessing the impact of oxidative stress, aging, and nutritional status on cellular energy production. Its applications extend to both basic research and clinical studies, providing insights into disease mechanisms and potential therapeutic interventions.