MethADP is primarily used in biochemical research to study the mechanisms of enzymes involved in nucleotide metabolism, particularly those related to ADP and ATP. It serves as a stable analog of ADP, allowing researchers to investigate the binding and catalytic processes of kinases, phosphatases, and other enzymes that interact with ADP. This compound is also valuable in understanding the regulation of cellular energy processes and signaling pathways. Additionally, MethADP is utilized in the development of inhibitors or modulators for therapeutic targets in diseases where nucleotide metabolism is disrupted, such as cancer or metabolic disorders. Its application extends to structural biology, where it aids in elucidating the three-dimensional structures of proteins complexed with nucleotide analogs.