ZD-1611 is primarily utilized in the field of medical research, particularly in the study of cardiovascular diseases. It functions as a potent endothelin receptor antagonist, making it valuable for investigating the role of endothelin in conditions such as hypertension, heart failure, and pulmonary arterial hypertension. By blocking endothelin receptors, it helps researchers understand the pathways involved in vasoconstriction and vascular remodeling, which are critical in the progression of these diseases. Additionally, ZD-1611 has been explored in preclinical studies to assess its potential therapeutic effects in improving blood flow and reducing vascular resistance, offering insights into novel treatment strategies for cardiovascular disorders.