GSK467 is primarily utilized in the field of medicinal chemistry and pharmacology as a selective inhibitor of the enzyme AAK1 (Adaptor-Associated Kinase 1). Its application is significant in research focused on understanding and modulating pathways related to neuropathic pain and other neurological disorders. By inhibiting AAK1, GSK467 helps in reducing the endocytosis of specific receptors involved in pain signaling, offering a potential therapeutic approach for managing chronic pain conditions. Additionally, it serves as a valuable tool in preclinical studies to explore the role of AAK1 in cellular processes and to develop novel treatments targeting this enzyme.