Endosidin 2 (ES2) is primarily used in biological research to study plant cell biology, particularly in understanding the mechanisms of endocytosis and vesicle trafficking. It is a valuable tool for investigating the role of the endomembrane system in plant growth and development. ES2 specifically targets the cellulose synthase complex, making it useful for studying cell wall biosynthesis and its regulation. Researchers also utilize ES2 to explore its effects on plant responses to environmental stresses, such as drought or pathogen attack, by disrupting normal cellular processes. Additionally, it serves as a chemical probe to identify and characterize proteins involved in endocytosis and membrane dynamics, contributing to advancements in plant biotechnology and crop improvement strategies.