Hexadecyl decanoate is widely used in the formulation of personal care products, particularly as an emollient and skin-conditioning agent. It helps to soften and smooth the skin by forming a protective barrier that locks in moisture, making it a common ingredient in lotions, creams, and moisturizers.

In the cosmetic industry, it serves as a thickening agent and stabilizer in various formulations, enhancing the texture and consistency of products. Its non-greasy feel and compatibility with other ingredients make it suitable for use in makeup, hair care products, and sunscreens.

Additionally, it is utilized in the production of lubricants and coatings, where its properties contribute to reducing friction and improving surface smoothness. Its stability and low volatility also make it a valuable component in industrial applications requiring long-lasting performance.