This metabolite is primarily studied in the context of pharmacokinetics and pharmacodynamics to understand the efficacy and safety of tofacitinib, a drug used to treat autoimmune conditions. It plays a crucial role in monitoring drug metabolism and optimizing dosage regimens for patients with rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Researchers analyze this metabolite to assess its contribution to the overall therapeutic effects and potential side effects, ensuring personalized and effective treatment strategies. Additionally, it is used in clinical trials and drug development to evaluate the metabolic pathways and long-term impact of tofacitinib therapy.