Tetranor-PGAM is primarily used in biomedical research as a biomarker for studying the metabolism and physiological effects of prostaglandins. It helps researchers understand the pathways and mechanisms involved in prostaglandin degradation, which is crucial for investigating inflammatory processes, cardiovascular health, and renal function. Additionally, it aids in the development of diagnostic tools and therapeutic strategies for conditions influenced by prostaglandin activity, such as hypertension and kidney disorders. Its role in metabolic studies also contributes to advancing knowledge in pharmacology and toxicology.