Used primarily in research settings as an active metabolite of the anabolic agent clenbuterol, 6-Hydroxy-3-methylindazole serves as a biomarker for detecting clenbuterol administration in doping control. It is valuable in anti-doping laboratories due to its prolonged presence in urine, allowing for extended detection windows. The compound aids in distinguishing between natural clenbuterol exposure and illicit use in sports. It is also utilized in analytical reference standards for mass spectrometry and chromatography in forensic and pharmaceutical testing.