Used in biochemical and metabolic studies to understand estrogen metabolism and detoxification pathways in the liver. Serves as a reference standard in analytical methods like HPLC and mass spectrometry for detecting estrogen conjugates in biological fluids. Employed in research on hormone excretion, as glucuronidated estrogens are primary forms eliminated in urine and bile. Also utilized in studies investigating the role of β-glucuronidase enzymes in hormone-dependent cancers, where deconjugation may influence local estrogen activity.