(–)-Sitagliptin Carbamoyl Glucuronide is primarily used in the field of pharmaceutical research and development. It serves as a key metabolite of sitagliptin, a drug commonly prescribed for the management of type 2 diabetes. This metabolite is formed through the glucuronidation process, which aids in the efficient elimination of the drug from the body. Researchers study this compound to better understand the metabolic pathways and pharmacokinetics of sitagliptin in the human body. This knowledge is crucial for assessing the drug's efficacy, safety, and potential side effects. Additionally, it aids in the development of improved therapeutic strategies and dosage regimens for diabetes treatment. The compound is also utilized in analytical chemistry for the development of bioanalytical methods, such as LC-MS/MS, to detect and quantify sitagliptin and its metabolites in biological samples, as well as for monitoring drug levels in patient blood to optimize dosing and minimize side effects.