Roflumilast N-Oxide is primarily used in the treatment of chronic obstructive pulmonary disease (COPD). It functions as a phosphodiesterase-4 (PDE-4) inhibitor, helping to reduce inflammation in the lungs. This action aids in decreasing the frequency of COPD exacerbations, improving lung function, and enhancing overall respiratory health. It is often prescribed for patients with severe COPD who experience chronic bronchitis and frequent flare-ups. Additionally, it may be used as a maintenance therapy to manage symptoms and improve quality of life for individuals with this condition. Its anti-inflammatory properties make it a valuable option in long-term COPD management.