BAR-501 is a synthetic bile acid derivative primarily utilized in medicinal chemistry to study the function of bile acid receptors (such as FXR), which play crucial roles in metabolism and the gastrointestinal system. It is employed in research for developing new therapeutics targeting energy metabolism-related diseases, including type 2 diabetes, obesity, and non-alcoholic fatty liver disease. Additionally, studies explore its applications in treating liver inflammation and biliary disorders. Preliminary research demonstrates BAR-501's potential to balance blood glucose and lipid levels, offering insights for more effective pharmaceutical development in preclinical trials and biochemical assays.