Tert-butyl(R)-(2-fluoro-3-iodopropyl)carbamate
98%
Reagent
Code: #244471
CAS Number
344413-81-6
blur_circular Chemical Specifications
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Molecular Information
Weight
303.11 g/mol
Formula
C₈H₁₅FINO₂
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Registry Numbers
MDL Number
MFCD30472100
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly the (R)-enantiomer in the development of chiral bioactive molecules where the fluorine atom enhances metabolic stability and binding affinity. The iodine moiety allows for further functionalization via cross-coupling reactions, making it valuable in medicinal chemistry for building complex molecular architectures. Its tert-butyl carbamate (Boc) group serves as a protected amine, enabling selective deprotection and coupling in multi-step syntheses of drugs targeting central nervous system disorders and oncology. Commonly employed in research settings for creating analogs of neuroactive compounds and kinase inhibitors.
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