2-FLUORO-5-HYDROXYMETHYLPHENYLBORONIC ACID
97%
Reagent
Code: #187296
Alias
2-Fluoro-5-(hydroxymethyl)benzeneboric acid
CAS Number
1072952-25-0
science Other reagents with same CAS 1072952-25-0
blur_circular Chemical Specifications
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Molecular Information
Weight
169.95 g/mol
Formula
C₇H₈|BFO₃
thermostat
Physical Properties
Melting Point
70-72°C
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Storage & Handling
Storage
2~8°C
description Product Description
Used in the synthesis of pharmaceutical intermediates, particularly in Suzuki-Miyaura cross-coupling reactions to construct biaryl compounds found in active drug substances. Serves as a building block in medicinal chemistry for developing fluorinated organic molecules with enhanced metabolic stability and binding affinity. Its boronic acid group enables rapid derivatization, while the fluorine atom acts as a bioisostere and improves pharmacokinetic properties. Commonly applied in research settings for drug discovery in oncology, CNS disorders, and antiviral therapies. Also utilized in the preparation of sensors and functional materials due to its selective reactivity and structural features.
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