BMS-986020
10mM in DMSO
Reagent
Code: #142622
CAS Number
1257213-50-5
blur_circular Chemical Specifications
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Molecular Information
Weight
482.53 g/mol
Formula
C₂₉H₂₆N₂O₅
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of idiopathic pulmonary fibrosis (IPF), BMS-986020 is a potent and selective antagonist of the lysophosphatidic acid receptor 1 (LPA1). This receptor plays a key role in fibrotic processes by mediating fibroblast recruitment, activation, and extracellular matrix deposition. By blocking LPA1, the compound helps reduce lung tissue scarring and slow disease progression. It has been evaluated in clinical trials to assess its efficacy in improving lung function and patient outcomes in IPF and other fibrotic conditions. Its development represents a targeted approach to treating fibrosis with potential application in systemic sclerosis and liver fibrosis.
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