Used in pharmaceutical research as a linker or spacer in the development of targeted drug delivery systems, particularly in antibody-drug conjugates (ADCs) and biotin-avidin based targeting. This molecule incorporates a biotin moiety ((3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl) linked via a pentanamido chain to a hydrophilic polyether (triethylene glycol) spacer ending in a carboxylic acid terminus. The biotin enables high-affinity binding to avidin or streptavidin for specific targeting, while the multiple ether bonds enhance solubility and stability in aqueous environments, improving pharmacokinetic properties of the conjugated drug.

Also explored in prodrug design to modulate release profiles and reduce off-target effects, and in immuno-oncology applications for cancer therapeutics.