tert-Butyl(2R,4S)-2-cyano-4-fluoropyrrolidine-1-carboxylate
98%
Reagent
Code: #155328
CAS Number
1932001-16-5
blur_circular Chemical Specifications
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Molecular Information
Weight
214.24 g/mol
Formula
C₁₀H₁₅FN₂O₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in the synthesis of antidiabetic drugs, particularly DPP-4 inhibitors like linagliptin. The chiral centers and functional groups allow for selective reactions in multi-step pharmaceutical manufacturing. The tert-butyl carbamate (Boc) group serves as a protecting group for the amine, enabling controlled deprotection during synthesis. The cyano and fluoro substituents contribute to the molecule's reactivity and binding properties in the final active pharmaceutical ingredient. Commonly employed in process chemistry for scalable and stereoselective production of pyrrolidine-based therapeutics.
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