tert-Butyl (R)-3-fluoro-4,4-dihydroxypiperidine-1-carboxylate

98%

Reagent Code: #153126
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CAS Number 2200580-26-1

science Other reagents with same CAS 2200580-26-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 235.25 g/mol
Formula C₁₀H₁₈FNO₄
inventory_2 Storage & Handling
Storage 2-8°C, drying away from light

description Product Description

Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of antidiabetic drugs such as DPP-4 inhibitors. Its stereochemistry and functional groups allow for selective reactions that are crucial in forming active pharmaceutical ingredients with high enantiomeric purity. The tert-butyl carbamate (Boc) group provides protection during peptide coupling or multistep synthesis, while the fluorine atom enhances metabolic stability and bioavailability in the final drug molecule. Commonly employed in research and process chemistry for constructing piperidine-based scaffolds in medicinal chemistry.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿1,670.00
inventory 250mg
10-20 days ฿3,790.00
inventory 1g
10-20 days ฿11,340.00

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tert-Butyl (R)-3-fluoro-4,4-dihydroxypiperidine-1-carboxylate
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Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of antidiabetic drugs such as DPP-4 inhibitors. Its stereochemistry and functional groups allow for selective reactions that are crucial in forming active pharmaceutical ingredients with high enantiomeric purity. The tert-butyl carbamate (Boc) group provides protection during peptide coupling or multistep synthesis, while the fluorine atom enhances metabolic stability and bioavailability in the fi

Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of antidiabetic drugs such as DPP-4 inhibitors. Its stereochemistry and functional groups allow for selective reactions that are crucial in forming active pharmaceutical ingredients with high enantiomeric purity. The tert-butyl carbamate (Boc) group provides protection during peptide coupling or multistep synthesis, while the fluorine atom enhances metabolic stability and bioavailability in the final drug molecule. Commonly employed in research and process chemistry for constructing piperidine-based scaffolds in medicinal chemistry.

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