Rucaparib (AG-014699,PF-01367338)
≥99%
Reagent
Code: #77760
CAS Number
459868-92-9
blur_circular Chemical Specifications
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Molecular Information
Weight
421.36 g/mol
Formula
C₁₉H₁₈FN₃OH₃PO₄
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Registry Numbers
MDL Number
MFCD17010269
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Storage & Handling
Storage
room temperature
description Product Description
Rucaparib is primarily used in the treatment of certain types of cancer, particularly ovarian cancer, fallopian tube cancer, and primary peritoneal cancer. It is especially effective in patients who have specific genetic mutations, such as BRCA1 or BRCA2. The drug works by inhibiting the PARP enzyme, which plays a crucial role in repairing DNA damage. By blocking this enzyme, Rucaparib prevents cancer cells from repairing their DNA, leading to their death. This targeted approach makes it a valuable option for patients with advanced or recurrent cancers who have limited treatment alternatives. Additionally, Rucaparib is sometimes used as a maintenance therapy to help prevent cancer from returning after initial treatment. Its ability to selectively target cancer cells with minimal impact on healthy cells has made it a significant advancement in precision medicine for cancer treatment.
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