TH5487 is primarily used in research settings to study and inhibit the activity of OGG1, an enzyme involved in DNA repair. By targeting OGG1, it helps scientists understand the enzyme's role in oxidative DNA damage and its potential implications in diseases such as cancer. This compound is particularly valuable in exploring therapeutic strategies that aim to disrupt DNA repair mechanisms in cancer cells, potentially enhancing the effectiveness of treatments like chemotherapy. Additionally, TH5487 serves as a tool in molecular biology to investigate the broader mechanisms of DNA damage response and repair pathways.