The DNA2 inhibitor C5 is primarily utilized in research focused on understanding DNA replication and repair mechanisms. It is particularly valuable in studies investigating the role of the DNA2 helicase/nuclease enzyme in these processes. By inhibiting DNA2, researchers can observe the effects on DNA end resection, a critical step in homologous recombination repair. This helps in elucidating the pathways involved in maintaining genomic stability. Additionally, it is used in cancer research to explore potential therapeutic strategies, as inhibiting DNA2 could sensitize cancer cells to DNA-damaging treatments like chemotherapy or radiation. Its application extends to studying aging and neurodegenerative diseases, where DNA repair mechanisms are often compromised.