Used primarily in the treatment of conditions related to excessive aldosterone activity, such as primary hyperaldosteronism and edema associated with heart failure, liver cirrhosis, or nephrotic syndrome. Acts as a competitive antagonist of the mineralocorticoid receptor, helping to reduce sodium reabsorption and potassium excretion in the kidneys. This leads to increased excretion of sodium and water while conserving potassium, making it useful in managing hypertension and hypokalemia. Also employed in diagnostic procedures to assess mineralocorticoid excess. Its potassium-sparing diuretic properties make it suitable for long-term management where electrolyte balance is a concern.