(tert-Butoxycarbonyl)-L-phenylalanylglycine (Boc-Phe-Gly-OH) is a protected dipeptide intermediate used in peptide synthesis. The Boc group protects the N-terminal amine of L-phenylalanine, preventing unwanted reactions during coupling steps, while the C-terminal glycine carboxylic acid allows for further extension of the peptide chain. It is particularly valuable in solid-phase peptide synthesis (SPPS) and solution-phase methods for constructing therapeutic peptides in pharmaceutical research. Additionally, it supports biochemical studies on peptide folding, protein interactions, and enzyme substrates due to its selective deprotection under acidic conditions without affecting the peptide backbone.