(Difluoro(phenylthio)methyl)trimethylsilane

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Reagent Code: #167465
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CAS Number 536975-49-2

science Other reagents with same CAS 536975-49-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 232.37 g/mol
Formula C₁₀H₁₄F₂SSi
badge Registry Numbers
MDL Number MFCD19442557
inventory_2 Storage & Handling
Storage 2-8°C, Inert Gas

description Product Description

Used as a fluorinating reagent in organic synthesis, particularly in the introduction of difluoromethylthio groups into bioactive molecules. Its silicon-containing structure enhances reactivity and selectivity in electrophilic fluorination reactions. Commonly applied in medicinal chemistry for the development of fluorinated pharmaceuticals, where the difluoro(phenylthio)methyl group acts as a lipophilic hydrogen-bond acceptor, improving metabolic stability and membrane permeability. Also employed in agrochemical synthesis to modify pesticide and herbicide candidates for improved efficacy and environmental persistence. The reagent’s stability and ease of handling make it suitable for late-stage functionalization in complex molecule synthesis.

Available Sizes & Pricing

Size Availability Unit Price Quantity
100mg
10-20 days ฿17,280.00
250mg
10-20 days ฿34,570.00
50mg
10-20 days ฿10,160.00

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(Difluoro(phenylthio)methyl)trimethylsilane
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Used as a fluorinating reagent in organic synthesis, particularly in the introduction of difluoromethylthio groups into bioactive molecules. Its silicon-containing structure enhances reactivity and selectivity in electrophilic fluorination reactions. Commonly applied in medicinal chemistry for the development of fluorinated pharmaceuticals, where the difluoro(phenylthio)methyl group acts as a lipophilic hydrogen-bond acceptor, improving metabolic stability and membrane permeability. Also employed in agro

Used as a fluorinating reagent in organic synthesis, particularly in the introduction of difluoromethylthio groups into bioactive molecules. Its silicon-containing structure enhances reactivity and selectivity in electrophilic fluorination reactions. Commonly applied in medicinal chemistry for the development of fluorinated pharmaceuticals, where the difluoro(phenylthio)methyl group acts as a lipophilic hydrogen-bond acceptor, improving metabolic stability and membrane permeability. Also employed in agrochemical synthesis to modify pesticide and herbicide candidates for improved efficacy and environmental persistence. The reagent’s stability and ease of handling make it suitable for late-stage functionalization in complex molecule synthesis.

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