5-Bromoisophthalic acid is primarily used as a building block in organic synthesis, particularly in the development of complex organic compounds. It serves as a key intermediate in the production of polymers and coordination polymers, which are essential in materials science for creating advanced materials with specific properties. Additionally, it is utilized in the synthesis of metal-organic frameworks (MOFs), which have applications in gas storage, separation, and catalysis. Its bromine atom makes it a valuable precursor for further functionalization in pharmaceutical research, enabling the creation of novel drug candidates. The compound is also employed in the preparation of ligands for catalysis and in the study of crystal engineering due to its ability to form stable crystalline structures.