YM-58790 is primarily utilized in research settings as a potent and selective inhibitor of the enzyme diacylglycerol kinase (DGK). Its application is significant in the study of cellular signaling pathways, particularly those involving lipid metabolism and second messenger systems. By inhibiting DGK, YM-58790 helps researchers understand the role of diacylglycerol (DAG) in processes such as immune response, cancer progression, and neuronal signaling. This compound is particularly valuable in pharmacological studies aimed at developing therapeutic strategies for diseases where DGK activity is dysregulated, including certain cancers and immune disorders. Its use in experimental models has provided insights into the modulation of T-cell activation and the potential for targeting DGK in immunotherapy.