BMS 193885
97%
Reagent
Code: #152578
CAS Number
186185-03-5
blur_circular Chemical Specifications
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Molecular Information
Weight
590.71 g/mol
Formula
C₃₃H₄₂N₄O₆
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Registry Numbers
MDL Number
MFCD16878998
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Storage & Handling
Storage
-20°C, dry
description Product Description
Used primarily in dermatological research, this compound functions as a selective antagonist of the histamine H4 receptor. It is employed to study inflammatory and pruritic (itch-related) conditions, particularly those involving allergic contact dermatitis and atopic dermatitis. Researchers utilize it to investigate the role of H4 receptors in immune cell signaling and skin inflammation pathways. Due to its ability to modulate itch responses in preclinical models, it has served as a tool compound in the development of new anti-itch therapies. It is not used clinically but supports the discovery and validation of targets for treating chronic skin disorders.
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