Used as a key reagent in organic synthesis, particularly in the preparation of sulfonamides, which are important in pharmaceutical development. It readily reacts with amines to form pyridine-3-sulfonamide derivatives, many of which exhibit biological activity, including antimicrobial and antiviral properties. Commonly employed in medicinal chemistry for modifying drug candidates to enhance solubility, stability, and target binding affinity. Also utilized in agrochemical synthesis and as a derivatizing agent in analytical chemistry for detection of amine-containing compounds.