Used as a silylating agent in analytical chemistry, particularly in gas chromatography-mass spectrometry (GC-MS) for the derivatization of polar compounds such as hydroxyl, carboxyl, and amino groups. It enhances the volatility and thermal stability of analytes, improving their detection and separation. Commonly applied in metabolomics and forensic analysis to analyze steroids, fatty acids, and drugs. Also employed in organic synthesis to protect functional groups during multi-step reactions.