Guanidine sulfate is widely used in biochemistry and molecular biology as a protein denaturant. It helps in unfolding proteins, making it valuable in studies of protein structure and function. Additionally, it is utilized in the purification of nucleic acids, particularly RNA, by disrupting secondary structures and facilitating isolation. In industrial applications, it serves as a stabilizer in the production of dyes and pharmaceuticals. It also finds use in the synthesis of organic compounds, acting as a reagent or catalyst in various chemical reactions.