Aldehyde dehydrogenase plays a crucial role in the detoxification of aldehydes in the body, converting them into less harmful carboxylic acids. This enzyme is particularly important in the liver, where it helps metabolize ethanol into acetic acid, aiding in the breakdown of alcohol. Beyond its role in alcohol metabolism, it is also involved in processing other environmental and dietary aldehydes, reducing their potential toxicity. In medical research, aldehyde dehydrogenase is studied for its connection to various diseases, including cancer and neurological disorders, as its activity can influence cellular processes like apoptosis and oxidative stress. Additionally, it is a target for drug development, particularly in treatments aimed at reducing alcohol dependency or managing conditions linked to aldehyde accumulation.