(S)-10-Allyl-4-ethyl-4,9-dihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

98%

Reagent Code: #232847
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CAS Number 185425-25-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 404.42 g/mol
Formula C₂₃H₂₀N₂O₅
badge Registry Numbers
MDL Number MFCD28138424
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

This compound is a camptothecin derivative that inhibits topoisomerase I, exhibiting anticancer activity particularly against colorectal, lung, and ovarian cancers. The allyl group at position 10 and ethyl group at position 4 enhance its water solubility and in vivo stability, improving drug delivery efficiency and reducing toxicity to normal cells. It is under development as a potent chemotherapeutic agent, especially in targeted delivery or nanotechnology-based systems to increase tumor accumulation and minimize side effects. Used in research for its potential as an antitumor agent via DNA intercalation, replication disruption, and apoptosis induction in leukemia and solid tumor models. Limited to laboratory and preclinical studies; not approved for therapeutic use.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿13,660.00
inventory 100mg
10-20 days ฿23,220.00
inventory 250mg
10-20 days ฿39,470.00

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