Picropodophyllotoxin
98%
Reagent
Code: #226219
Alias
Related CAS number: 477-47-4
CAS Number
17434-18-3
science Other reagents with same CAS 17434-18-3
blur_circular Chemical Specifications
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Molecular Information
Weight
414.40528 g/mol
Formula
C₂₂H₂₂O₈
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Registry Numbers
MDL Number
MFCD01742647
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Storage & Handling
Storage
2-8℃, shielded from light, sealed
description Product Description
Used in cancer research due to its ability to inhibit the insulin-like growth factor 1 receptor (IGF-1R), which plays a role in tumor cell proliferation and survival. Shows potential as an anti-cancer agent, particularly in studies involving glioblastoma and other solid tumors. Demonstrates cytotoxic effects on cancer cells while sparing normal cells, making it a candidate for targeted therapy development. Also investigated for its role in inducing apoptosis and cell cycle arrest in malignant cells.
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