Picropodophyllotoxin

10mM in DMSO

Reagent Code: #224176
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CAS Number 477-47-4

science Other reagents with same CAS 477-47-4

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Weight 414.41 g/mol
Formula C₂₂H₂₂O₈
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MDL Number MFCD01742647
inventory_2 Storage & Handling
Storage -20°C

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Used in cancer research due to its ability to inhibit the insulin-like growth factor 1 receptor (IGF-1R), which plays a key role in tumor cell proliferation and survival. Shows potential as an antitumor agent, particularly in studies involving glioblastoma, melanoma, and other solid tumors. Its mechanism involves inducing cell cycle arrest and promoting apoptosis in cancer cells without significant toxicity to normal cells, making it a candidate for targeted cancer therapy development.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿7,200.00

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Picropodophyllotoxin
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Used in cancer research due to its ability to inhibit the insulin-like growth factor 1 receptor (IGF-1R), which plays a key role in tumor cell proliferation and survival. Shows potential as an antitumor agent, particularly in studies involving glioblastoma, melanoma, and other solid tumors. Its mechanism involves inducing cell cycle arrest and promoting apoptosis in cancer cells without significant toxicity to normal cells, making it a candidate for targeted cancer therapy development.
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