Used in dermatology as a key active ingredient in topical treatments for genital warts and other benign skin growths due to its antimitotic properties. It works by inhibiting cell division, leading to the destruction of rapidly dividing cells such as those infected with human papillomavirus (HPV). Commonly applied by healthcare professionals in clinical settings for the management of recurrent respiratory papillomatosis and plantar warts. Also investigated for its potential in anticancer therapies owing to its ability to interfere with microtubule assembly, similar to other spindle inhibitors. Its derivatives, such as etoposide and teniposide, are widely used in chemotherapy, highlighting its importance in oncology drug development.