Used in topical treatments for actinic keratosis, a precancerous skin condition caused by prolonged sun exposure. The compound works by promoting cell death in abnormal skin cells and stimulating an immune response in the treated area. It is valued for its ability to target damaged cells with minimal impact on surrounding healthy tissue. Its mechanism includes activation of protein kinase C, leading to rapid cellular effects that help clear lesions. Due to its potent biological activity, it is formulated in low concentrations for clinical use.