10-Nitrocamptothecin
Analytical reference substance, ≥98% (HPLC)
Reagent
Code: #216563
CAS Number
86639-62-5
science Other reagents with same CAS 86639-62-5
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Molecular Information
Weight
393.35 g/mol
Formula
C₂₀H₁₅N₃O₆
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Registry Numbers
MDL Number
MFCD06656294
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an experimental antitumor agent, particularly in the treatment of solid tumors such as colon, lung, and liver cancers. It functions by inhibiting topoisomerase I, an enzyme critical for DNA replication and cell division, leading to cancer cell death. Its nitro group enhances stability and may improve tissue penetration, making it a candidate for targeted chemotherapy. Research also explores its potential in drug delivery systems like nanoparticles to increase efficacy and reduce side effects.
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