10-Nitrocamptothecin

Analytical reference substance, ≥98% (HPLC)

Reagent Code: #216563
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CAS Number 86639-62-5

science Other reagents with same CAS 86639-62-5

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Weight 393.35 g/mol
Formula C₂₀H₁₅N₃O₆
badge Registry Numbers
MDL Number MFCD06656294
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as an experimental antitumor agent, particularly in the treatment of solid tumors such as colon, lung, and liver cancers. It functions by inhibiting topoisomerase I, an enzyme critical for DNA replication and cell division, leading to cancer cell death. Its nitro group enhances stability and may improve tissue penetration, making it a candidate for targeted chemotherapy. Research also explores its potential in drug delivery systems like nanoparticles to increase efficacy and reduce side effects.

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Size Availability Unit Price Quantity
inventory 20mg
10-20 days ฿6,400.00

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10-Nitrocamptothecin
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Used as an experimental antitumor agent, particularly in the treatment of solid tumors such as colon, lung, and liver cancers. It functions by inhibiting topoisomerase I, an enzyme critical for DNA replication and cell division, leading to cancer cell death. Its nitro group enhances stability and may improve tissue penetration, making it a candidate for targeted chemotherapy. Research also explores its potential in drug delivery systems like nanoparticles to increase efficacy and reduce side effects.
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