Used in cancer research due to its ability to inhibit topoisomerase I, an enzyme involved in DNA replication. This inhibition leads to DNA damage in rapidly dividing cells, making it a potential candidate for antitumor therapy. It has shown activity against various cancer cell lines in preclinical studies. Its lipophilic nature allows better cellular uptake compared to some other camptothecin derivatives, enhancing its cytotoxic effects. Research also explores its use in drug delivery systems like nanoparticles to improve stability and target tumor tissues more effectively.