4-Hydroxycephalotaxine
Analytical reference substance, ≥98% (HPLC)
Reagent
Code: #196625
CAS Number
84567-08-8
blur_circular Chemical Specifications
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Molecular Information
Weight
331.36 g/mol
Formula
C₁₈H₂₁NO₅
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Registry Numbers
MDL Number
MFCD20260901
thermostat
Physical Properties
Melting Point
135-137 °C
Boiling Point
533.3±50.0 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used in the synthesis of anticancer agents, particularly as a key intermediate in the production of homoharringtonine and harringtonine, which are employed in the treatment of chronic myeloid leukemia (CML). Its structural complexity makes it valuable in developing derivatives with improved pharmacological activity. Also studied for its potential in inhibiting protein synthesis in cancer cells, contributing to apoptosis. Research explores its role in drug development for hematologic malignancies due to its ability to interfere with ribosomal function.
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