(-)-Epipodophyllotoxin
≥98%
Reagent
Code: #184344
CAS Number
4375-07-9
science Other reagents with same CAS 4375-07-9
blur_circular Chemical Specifications
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Molecular Information
Weight
414.41 g/mol
Formula
C₂₂H₂₂O₈
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Registry Numbers
MDL Number
MFCD01725610
thermostat
Physical Properties
Melting Point
160.3 °C
Boiling Point
597.9 °C at 760 mmHg
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Storage & Handling
Density
1.2649 (rough estimate)
Storage
2-8°C, sealed, dry
description Product Description
Used primarily as a key intermediate in the synthesis of chemotherapeutic agents like etoposide and teniposide. These drugs are widely employed in the treatment of various cancers, including testicular cancer, small cell lung cancer, and certain types of leukemia and lymphoma. The compound contributes to the inhibition of topoisomerase II, an enzyme involved in DNA replication and repair, leading to cancer cell death. Its natural origin and specific mechanism make it valuable in oncology drug development.
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