Osilodrostat is primarily used in the treatment of Cushing's syndrome, a condition caused by excessive levels of cortisol in the body. It works by inhibiting the enzyme 11β-hydroxylase, which is involved in the production of cortisol in the adrenal glands. By blocking this enzyme, Osilodrostat helps to reduce cortisol levels, alleviating symptoms such as weight gain, high blood pressure, and glucose intolerance. It is particularly beneficial for patients who are not suitable candidates for surgery or who have not responded adequately to other treatments. The medication is administered orally and requires careful monitoring to ensure cortisol levels are maintained within a safe range, avoiding potential side effects like adrenal insufficiency.