Used primarily in research settings to study drug-induced liver injury, as it was withdrawn from clinical use due to hepatotoxicity. Serves as a model compound for investigating metabolic activation and immune-mediated adverse drug reactions. Also employed in studies examining the role of cytochrome P450 enzymes in drug metabolism, particularly CYP2C9, due to its metabolic pathway involving reactive intermediates. Its structure has been used in the design of probes for enzyme inhibition and metabolic stability testing.