1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one

98%

Reagent Code: #192243
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CAS Number 350678-63-6

science Other reagents with same CAS 350678-63-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 405.42 g/mol
Formula C₂₃H₂₀FN₃O₃
thermostat Physical Properties
Boiling Point 665.1±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.30±0.1 g/cm3(Predicted)
Storage -20°C, Sealed, Dry

description Product Description

Used in pharmaceutical research as a potent inhibitor of cytochrome P450 enzymes, particularly CYP3A4, this compound serves as a lead structure in developing agents that modulate drug metabolism. Its ability to selectively bind and inhibit key metabolic enzymes makes it valuable in enhancing the bioavailability of co-administered drugs. It has also shown potential in studies targeting hormone-dependent conditions due to its interaction with steroidogenic pathways. Additionally, its structural features support investigation in central nervous system disorders, where enzyme inhibition may influence neurochemical balance. Research applications include in vitro assays, metabolic stability tests, and pharmacokinetic enhancement strategies.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿10,990.00
inventory 25mg
10-20 days ฿28,590.00

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1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one
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Used in pharmaceutical research as a potent inhibitor of cytochrome P450 enzymes, particularly CYP3A4, this compound serves as a lead structure in developing agents that modulate drug metabolism. Its ability to selectively bind and inhibit key metabolic enzymes makes it valuable in enhancing the bioavailability of co-administered drugs. It has also shown potential in studies targeting hormone-dependent conditions due to its interaction with steroidogenic pathways. Additionally, its structural features support investigation in central nervous system disorders, where enzyme inhibition may influence neurochemical balance. Research applications include in vitro assays, metabolic stability tests, and pharmacokinetic enhancement strategies.
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