Used primarily in pharmaceutical research for its ability to modulate drug metabolism. It is known to inhibit certain cytochrome P450 enzymes, particularly CYP3A4, which plays a key role in the breakdown of many drugs in the body. This inhibition can increase the bioavailability and prolong the effects of co-administered medications, making it valuable in studies focused on improving drug efficacy and reducing dosage requirements. Also investigated for potential interactions with statins, calcium channel blockers, and immunosuppressants. Its derivatives are explored for use in enhancing the performance of oral therapeutics by reducing first-pass metabolism. Additionally, it serves as a reference compound in metabolic studies involving grapefruit juice components, due to its presence in citrus fruits and contribution to the "grapefruit juice effect."