LHVS is primarily utilized in the field of biochemistry and molecular biology as a selective inhibitor of cysteine cathepsins, which are enzymes involved in protein degradation. Its application is significant in research focused on understanding the role of these enzymes in various cellular processes, including apoptosis, immune response, and extracellular matrix remodeling. LHVS is also used in studies related to cancer, as cysteine cathepsins are often overexpressed in tumor cells and contribute to tumor progression and metastasis. Additionally, it serves as a tool in the development of therapeutic agents targeting cathepsin-related diseases, such as osteoporosis, arthritis, and certain neurodegenerative disorders. In drug discovery, LHVS helps in validating cathepsins as potential drug targets by selectively inhibiting their activity and observing the resulting biological effects.