Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and antiviral drugs. Its rigid biphenyl-cyclopropane structure enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate lipophilicity and conformational restraint. Also utilized in the preparation of fluorinated analogs to improve bioavailability and pharmacokinetic profiles.