Trans-3-Aminocyclobutanecarboxylic acid is primarily used in the field of medicinal chemistry and drug development. It serves as a valuable building block for the synthesis of various pharmaceutical compounds. Its unique cyclobutane ring structure, combined with the amino and carboxylic acid functional groups, makes it a versatile intermediate in the creation of peptidomimetics and bioactive molecules. Researchers utilize it to design and develop potential therapeutic agents, particularly in the areas of enzyme inhibitors and receptor modulators. Additionally, it has been explored in the study of conformationally constrained peptides, which are important for understanding protein-protein interactions and developing new drugs with enhanced stability and specificity.