Cyclobutylideneacetonitrile is primarily utilized in organic synthesis as a versatile intermediate for the construction of complex molecular structures. Its unique cyclobutylidene moiety makes it valuable in the development of pharmaceuticals, particularly in the synthesis of bioactive compounds and drug candidates. The compound is also employed in the preparation of specialized polymers and materials, where its reactivity enables the creation of novel chemical architectures. Additionally, it serves as a key building block in the synthesis of natural products and fine chemicals, contributing to advancements in medicinal chemistry and material science.