Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals where cyclobutane derivatives show potential in drug development for neurological and inflammatory conditions. Its structural rigidity and functional handles allow for selective transformations, making it valuable in building complex molecules. Also employed in agrochemical research for designing novel pesticides with improved stability and target specificity. The trans configuration enables stereocontrolled reactions, enhancing purity and efficacy in final products.